targeting advanced glycation end products in cardiac surgery: the unexplored alternative
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منابع مشابه
Targeting Advanced Glycation End Products in Cardiac Surgery: The Unexplored Alternative.
Copyright © 2016, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work i...
متن کاملAdvanced glycation end products
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed. In the last years advanced glycation end products (AGEs) have received particula...
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BACKGROUND Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE-ligand engagement. METHODS We examined the association between N(ε)-(carboxymethyl)lysine (CML), a prom...
متن کاملAdvanced glycation end products and the kidney
Bohlender, Jürgen M., Sybille Franke, Günter Stein, and Gunter Wolf. Advanced glycation end products and the kidney. Am J Physiol Renal Physiol 289: F645–F659, 2005; doi:10.1152/ajprenal.00398.2004.—Advanced glycation end products (AGEs) are a heterogeneous group of protein and lipids to which sugar residues are covalently bound. AGE formation is increased in situations with hyperglycemia (e.g....
متن کاملAdvanced glycation end products in diabetic corneas.
PURPOSE Corneal complications are often associated with diabetes mellitus and can be vision threatening. Corneas in diabetic patients are exposed to increased glucose concentration despite cornea's avascular property, and this condition may contribute to the accumulation of advanced glycation end products (AGEs). The focus of this study was to examine the role of AGEs in the pathogenesis of dia...
متن کاملAdvanced glycation end-products in diabetic nephropathy
Throughout the industrialized (well-fed) Adverse effects of hyperglycaemia, once thought an epiphenomenon in the pathogenesis of diabetic microworld, diabetes mellitus is the most prevalent cause of end-stage renal disease (ESRD). Diabetic nephropathy and macrovascular complications, presently are a central focus of active clinical and basic investigation is as likely to develop in long-duratio...
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عنوان ژورنال:
research in cardiovascular medicineجلد ۵، شماره ۲، صفحات ۰-۰
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